Dangerous to run tires backwards?

[WhipE350]

Originally Posted by blue2000s

Don't think that the HTRZIII is anything close to an all season tire. They're way too hard when cold. The different sections are for predictable, stable handling in combination with safe water removal.

True they certainly aren't all season, I've driven several winters in them and I don't 'do' snow. But putting aside whatever the inner tread pattern is, the outer tread looks very much directional and one is always going in a direction that seems backwards. I have heard that some tire manufactures (but I haven't seen one) make a left and right so that this doesn't occur.