I am by far not a car audio pro, but I learned quite a bit after installing several HUs and speakers over the years.
Yes, Ohm is important, but overrated. Mixing 2Ohm speakers (OEM) with 4Ohm speakers is useless. So looking into the speakers Ohm and HU Ohm is the first step. Mixing 3 Ohm and 4 Ohm can be done and sometimes it is even the OEM speaker set-up in a 3 way system.
Next step: What do you want, a coax speaker (combined (Mid/tweeter) system or 3-way (bass, mid, tweeter) system. They are more expensive and more difficult to install and prepare.
I chose a 3 way speaker system and combined it with a mini subwoofer.
As I run the overpriced PCCM+, I did NOT want to save a buck on speakers.
So all speakers, mini sub and prep material costs came up to half a PCCM+.
Was it worth the hassle? YES.
Was it necessary? NO.
I changed from a single Din HU with 4 (!) COAX speaker to a PCCM+ with a 3-way speaker system plus sub.
Biggest impact has the sub.
2nd biggest impact has the damping.
3rd biggest impact has the switch to a 3-way system. VAS liter volume of the speakers is something, you want to look at. I found HERTZ was offering the best speaker system in that case for our Boxsters and their door and dash locations.
Most of the installation is pictured in my Seal Greey thread.