I remember as a little kid in the early 60's (maybe even late 50's) seeing the original Globetrotters, with Meadowlark Lemon (now 81!). They did all kinds of gigs, big and small, and came to the local high school, playing around with/"against" the varsity team. Sweet Georgia Brown they were great.
But Jager's right...they'd get their butts kicked in the NBA.