If you swap the lot, the S hub uses a larger wheel bearing so you need use different axles.
The S discs and calipers will just bolt on if you don't care about the handbrake. It's a negligible upgrade, couple of mm thicker and larger disc. Not worth losing the handbrake over in my opinion.
I've just cobbled together a big brake upgrade on the rear of mine using 991 GT3 Cup discs (380mm) and Lotus Evora 400 calipers.