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You'd be surprised at the number of abondoned ghost towns in the middle of America that resulted from the interstate and highway system bypassing small towns.

When I was a child, my grandparents took me to a family reunion in grandmas home town of Eagleville, MO. The "highway" leading to the town was used so little that tall weeds were growing up through cracks all over the road. I think there were three occupied homes out of maybe 100 and all businesses boarded up. I thought for sure that it would be completely desolate by now, but it has taken a surprising turn for the better and has even grown since.