If it was a current model M3 vs an Accord v6 coupe, I would have to attest the M3's inabilities to driver deficiency. I cant count the amount of times I have read about someone cleaning up on a faster car simply because they know how to shift and drive.
As far as other cars go, Im surprised no one talks about TVR anymore. I have driven a few models and they are all amazing inspirations to the human driving spirit. And if you're left handed, you'll LOVE em LOL
I suppose its hard (or maybe impossible) to register an alternate position car here in the states? A few lucky folks got to register their mclarens and those guys sit in the middle!