We just got back from San Fran and had the best time.
I would highly recommend
www.greatpacifictour.com and do the Carmel trip. It was great. Cynthia knew all the best stops.
We also did the Movie City Tour. Another great day including trip to Golden gate park and Lucas Film Studio.
You don't want to miss the Alcatraz tour. It is a must see.
We also went to 2 wineries but I don't remember the names.