Another WAG. So that doesn't look like a scratch to me. It looks like the window tint is wrinkled/failing? And there are some small bubbles on the bottom left end? I think the grinding noise might be a separate issue from a failing regulator?
Cause might be something stuck between the door rubber and the glass? Although raising/lowering the glass would/should make a vertical line, not curved.
Try peeling the tint off first and see what shape the glass is in underneath.
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