Two years ago, right after a thunderstorm. Had to be more cautious due to wet surface conditions. great ride, as is Cherohala Skyway which others have mentioned. Another option, much more challenging, is the Diamondback
Diamond Back Loop (226 & 226A) | North Carolina Motorcycle Roads and Rides | MotorcycleRoads.com
Had me white-knuckled and obeying the yellow turn speeds.
Two great sites for exploring the twisties:
2562 Motorcycling Roads United States
MotorcycleRoads.US - Great Motorcycle Roads in the US
DBear