Had it happen to me last spring after hibernating for a couple months. I had a misfire on cylinder 2 and additionally cylinder 3 on two separate occasions. So, since my ride was due for its 60K maintainence anyway, I decided to just replace all my plugs, coils and tubes. Also helped that I had a few guys on renntech help me out with suggestions of a bottle of Techtron and an oil change. Ran fine after resetting the codes.
