That's a LONG freakin' drive! I can't say my ass would be able to take that--I get whiny after just a drive up and down to San Francisco!
As for elevation, I can feel the difference in horsepower even when just driving out on I-8 to Viejas (Alpine). I think the sign said that it was about 2000 ft. MSL, which isn't a lot, but it definitely took some snort out of the car.
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