I've had my '01 on two road trips over the past couple of months. One about 800 miles and the other about 1,950 miles. The car did great. The only downside might be the ride over poorly maintained highways... gets a little old after a while.
I did my usual pre-trip stuff - tires, check all fluids, wash, and wax. I checked the oil (via the dash gauge) with every fill-up. Averaged about 31mpg on the 800 mile trip and 32mpg (best of 33.7) on the 1,950.